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Scientists in Israel have created a model of a human embryo from stem cells, without using sperm, eggs or a womb. A team at Israel's Weizmann Institute of Science made the model, which resembles an embryo at day 14, when it acquires internal structures but before it lays down the foundations for body organs, and the work was published in the journal Nature. But the scientists involved said it would take a long time yet to create an embryo from scratch. Team leader Jacob Hanna said the team took stem cells derived from adult human skin cells, as well as others cultured in the lab, then reverted the cells to an early state.They then manipulated them to make a model of an embryo, rather than an actual or synthetic one. "The question is, when does an embryo model become considered an embryo? When that happens, we know the regulations. At the moment we are really, really far off from that point," Hanna said. However, they said the work could open the door to new ways to test the effect of drugs on pregnancies, better understand miscarriages and genetic diseases, and maybe grow transplant tissues and organs. "They are not identical. There are differences from human embryos, but still, this is the first time, if you open an atlas or a textbook, you can say - yeah I can really see the similarity between them," said Hanna. "In about 1 percent of the aggregates we can see that the cells start differentiating correctly, migrating and sorting themselves into the correct structure, and the farthest we could get is day 14 in human embryo development," he said. Their next goal, Hanna said, is to advance to day 21 and also reach a threshold of a 50 per cent success rate. Magdalena Żernicka-Goetz, a professor of development and stem cells at the University of Cambridge, said the study joins six other similar human embryo-like models published from teams around the world this year, including from her lab. "None of these models fully recapitulate natural human development but each adds to ways in which many aspects of human development can now be studied experimentally," she said. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Bryan Kohberger is believed to have broken into the home of a female student and then installed security cameras to spy on her in the months before he allegedly killed four other students in a horror attack in Moscow, Idaho. The 28-year-old criminology PhD student had befriended the woman after he moved to Pullman, Washington state, to begin a graduate program in criminal justice at Washington State University (WSU), according to a source. One day, the woman returned to her apartment and found that someone had broken in and moved items around the home – but that nothing was missing. Since nothing was taken, the woman decided not to call the police but instead called her new friend Mr Kohberger and asked him to come over. Mr Kohberger allegedly offered to install a video security system inside her home and the woman agreed. Following its installation, investigators believe Mr Kohberger used the security cameras to spy on the woman as – knowing her wifi password – he was able to tap into the cameras when within close proximity to the apartment. The bombshell allegation was revealed for the first time in an NBC Dateline episode titled “The Killings on King Road”, which reported that Mr Kohberger is now a strong suspect in the initial break-in. Months later, on 13 November, Mr Kohberger is accused of breaking into an off-campus home in Moscow, Idaho, and stabbing to death Madison Mogen, Kaylee Goncalves, both 21, and Xana Kernodle and Ethan Chapin, both 20. Former FBI profiler Greg Cooper told Dateline that the incident was a “step in progression” for Mr Kohberger to move from breaking into a home when no one was in to allegedly breaking in when multiple people were home at the King Road address that deadly night in November. “I would expect that he orchestrated the whole thing, he was not looking at her as a potential victim necessarily,” said Mr Cooper. “But he orchestrated it so that she would come to him and that he would be able to help her. It is another level of power and domination and control over another person. “The hero image that he can portray. ‘You’ve got this problem, I’m here to solve the problem for you and to make it better for you.’” In the Dateline episode, sources also revealed that Mr Kohberger’s sister was growing suspicious that her brother could have been responsible for the murders when the family gathered to spend the holidays together. In mid-December, Mr Kohberger left his student rental home in Pullman, Washington, to travel cross country with his father back to the family home in Albrightsville, Pennsylvania, for the holidays. During his time at home, his family members noticed that he was behaving somewhat bizarrely. The source said that Mr Kohberger was constantly wearing latex gloves, including inside their own home. One of his two older sisters began to wonder if he could have played a part in the murders – and, at one point, she raised her concerns with her other family members. She “loudly pointed out” that, at the time of the murders, her brother was living just a few miles from the crime scene and that he drove a white Hyundai Elantra – the make and colour of vehicle at the centre of the investigation. Along with his bizarre tendency to wear latex gloves at all time, she believed that the family should consider that Mr Kohberger might have killed the four victims, the source said. Mr Kohberger’s father allegedly defended his son and insisted he could not have been involved. But her suspicions were so great that – at one point – several family members searched Mr Kohberger’s white Hyundai Elantra for possible evidence of the crime, the source said. By that point, police said Mr Kohberger had already been spotted cleaning his car out with bleach and so the family members didn’t find anything of note, the source said. It is not clear if Mr Kohberger was aware of his family members’ suspicions that he could have been behind the murders – or what potential prior behaviour may have led his own sister to suspect him capable of carrying out such a brutal crime. Soon after, in the early hours of 30 December, law enforcement swooped on the family home and arrested him for the murders. At the time of his arrest, the source said Mr Kohberger was wide awake standing in the kitchen wearing latex gloves and putting his personal trash in plastic bags to take it out to a neighbour’s trash can. An attorney close to Mr Kohberger’s family declined to comment on the revelations to Dateline. On Monday (22 May), he will appear in court for his arraignment on four counts of first-degree murder and burglary. The 28-year-old is now scheduled to be arraigned in Latah County Court in Moscow, Idaho, where he is expected to enter a plea on the charges. Mr Kohberger had been due to appear in court for a week-long preliminary hearing on 26 June, where the prosecution would lay out the case and evidence against the suspect. However, last Tuesday, a grand jury indicted Mr Kohberger on the charges, paving the way for the case to proceed without and leading to the cancellation of the preliminary hearing. Mr Kohberger is accused of breaking into the student home in the early hours of 13 November and stabbing the four students to death in a horror attack that rocked the college town of Moscow and sent shockwaves across America. The motive remains unknown and it is still unclear what connection the WSU PhD student had to the University of Idaho students – if any – prior to the murders. However, the affidavit, released in January, revealed that Mr Kohberger’s DNA was found on a knife sheath left behind at the scene of the murders. It also revealed that his white Hyundai Elantra was caught on surveillance footage at the crime scene and that one of the surviving roommates came face to face with the killer – masked, dressed in head to toe black and with bushy eyebrows – as he left the home in the aftermath of the murders. New details have also emerged about what was found during an initial search of his apartment and a rental storage unit. The court documents show that two items found in his apartment tested positive for blood. The two items were a mattress cover on the bed and an uncased pillow, both of which had visible “reddish brown stains”. The documents do not reveal who the blood belongs to. Investigators seized a string of other items from his home including possible human and animal hair strands, a disposable glove and a computer. The murder weapon – a fixed-blade knife – has still never been found. As a criminal justice PhD student at WSU, Mr Kohberger lived just 15 minutes from the victims over the Idaho-Washington border in Pullman. He had moved there from Pennsylvania and began his studies there that summer, having just completed his first semester before his arrest. Before this, he studied criminology at DeSales University – first as an undergraduate and then finishing his graduate studies in June 2022. While there, he studied under renowned forensic psychologist Katherine Ramsland who interviewed the BTK serial killer and co-wrote the book Confession of a Serial Killer: The Untold Story of Dennis Rader, the BTK Killer with him. He also carried out a research project “to understand how emotions and psychological traits influence decision-making when committing a crime”. Now, the criminology PhD student is set to appear in Latah County Courthouse in Idaho for his preliminary hearing on 26 June. He is facing life in prison or the death penalty for the murders that have rocked the small college town of Moscow and hit headlines around the globe. Read More Bryan Kohberger – live: Idaho murders suspect faces arraignment over quadruple stabbing today Who is Bryan Kohberger? The criminology graduate being arraigned over the Idaho college murders Four students stabbed to death, a weeks-long manhunt and still no motive: What we know about the Idaho murders

By Jarrett Renshaw (Reuters) -The White House on Friday said that Tesla model chargers would be eligible for billions of

Republican Rep. Jim Jordan is trying to draw a sharp contrast with his chief competitor for the speakership, arguing that he would be a more effective messenger for his party to the American public as he tries to win Republican holdouts ahead of next week's pivotal vote.