Germany pulled off the biggest upset of its basketball existence and hardly anyone back home seemed to notice

The U.S. Food and Drug Administration on Tuesday approved Amgen's biosimilar version of Johnson & Johnson's blockbuster psoriasis

Kai Cenat is keen to appear alongside MrBeast in a video

Gayle King scrambled to find a dress for Beyonce's Las Vegas concert but managed to dazzle in a sexy silver number

Two Florida police officers have been shot and critically injured during a traffic stop

After the alert level on the Popocatépetl volcano was lowered in early June, the name of Mexico's most famous volcano might start fading from news headlines

Three Ukrainian pilots, including a well-known pilot who went by the call sign "Juice," have died in a plane crash, the Ukrainian Air Force said on Saturday.

Pope Francis has a fever that caused him to clear his schedule on Friday morning, the Vatican said, nearly two months after the 86-year-old...

Former president Donald Trump has arrived in Miami ahead of his arraignment on 37 charges over his handling of classified documents after leaving the White House. The former president flew from Newark Liberty International Airport to Miami International Airport yesterday afternoon and spent the night at his Mar-a-Lago estate – the Florida home where he is accused of hoarding troves of classified papers, including national defence information. Mr Trump will appear for his arraignment in a federal courtroom in downtown Miami this afternoon, before flying straight back to New Jersey where he has announced plans to deliver remarks tonight at his golf club. While Mr Trump gave defiant speeches at two Republican state conventions on Saturday in Georgia and North Carolina, his former attorney general Bill Barr has said that – after reviewing the indictment – he believes Mr Trump is “toast”. “If even half of it is true, then he’s toast,” he said of the 49-page indictment. Mr Trump responded by lashing out at Mr Barr both on Truth Social and during a sprawling interview on Roger Stone’s radio show where he branded the former top prosecutor a “gutless pig”. Read More Trump’s favourability rises in poll despite indictment Jonathan Turley tells Fox News the Trump indictment is ‘extremely damning’ and a ‘hit below the waterline’ Trump, allies escalate attacks on criminal case as history-making court appearance approaches Is Donald Trump going to prison?

Palestinian militants fire barrages into Israel after it targets Islamic Jihad rocket launchers.

In 2012, during the seventh season of 'Keeping Up with the Kardashians', Kanye made his debut 'reality TV' appearance

Google says it has made a significant step in identifying disease-causing genes, which could help spot rare genetic disorders. A new model named AlphaMissense is able to confidently classify 89 per cent of all possible “missense” variants in genes, identifying whether they are likely to cause diseases or benign. That compares with just 0.1 per cent of all missense variants that have been confidently classified by human experts. Missense variants happen when a single letter is substituted in the DNA, which in turn leads to proteins with a different amino acid. That small change can have significant effects – Google likened it to the way that changing a letter in one word can change the meaning of the whole sentence. Most of those variants are benign: the average person has more than 9,000 of them. But some of them can be disastrous, leading to rare genetic diseases. The new AlphaMissense looked at existing information about missense variants, and how commonly they are seen in humans and closely-related primates. It looked for those that were rarely seen, classifying them as pathogenic, and from that was able to use that information to analyse other protein sequences – giving not just a verdict on whether they were likely to cause problems, but also how confident it was. Experiments, conducted by humans, which look to find those mutations are expensive and slow: they require people to examine each unique protein and designed separately. Google says that the new system means that researchers can “preview” those results for thousands of proteins at a time, helping them decide where to focus. The company has used its systems to release a vast catalogue of “missense” mutations, so that researchers can learn about what effect they have. In some cases, those variations can lead to conditions such as cystic fibrosis, sickle-cell anaemia, or cancer, and understanding them could be key to researchers studying ways to treat or prevent those diseases. It is just the latest health breakthrough from Google’s Deepmind division, which is looking to use artificial intelligence to both identify and treat a variety of conditions. The new system was built on AlphaFold, the breakthrough model that helped unfold proteins, the building blocks of life. The research is described in a new paper, ‘Accurate proteome-wide missense variant effect prediction with AlphaMissense’, published in the journal Science. The catalogue is being made “freely available to the research community”, Google said, and the company will release the code behind the AI system. Read More BBC removes some Russell Brand content as monetisation suspended on YouTube Google Bard can now link to Gmail and other apps to help with responses Long-form video content is here to stay, says YouTube UK boss