Centenarians tend to have lower levels of glucose, creatinine and uric acid from their sixties onwards, according to the largest study of its kind that may lead to a simple blood test to predict a person’s chance of reaching 100. The research, published on Monday in the journal GeroScience, is the biggest to date to measure and follow up the levels of different molecules in the blood of people born between 1893 and 1920. Scientists, including those from Karolinska Institutet, assessed the data on blood molecules from over 44,500 Swedes who underwent clinical testing between 1985 and 1996 and followed up till 2020. They focused specifically on people born between 1893 and 1920, who were between 64 and 99 years old when their blood samples were first tested, and followed them up as they grew closer to 100 years of age. About 1,200 individuals in the study, or about 2.7 per cent of the participants, reached 100. Researchers compared this subset’s data with those of their peers who were younger than them. The analysis found 12 blood-based molecules associated with metabolism, inflammation as well as liver and kidney function, that were also linked to ageing or mortality in previous studies. These molecules included total cholesterol and glucose as markers of metabolism, uric acid indicating inflammation levels, enzymes indicative of liver health and creatinine as a measure of kidney health. Researchers also looked at albumin and iron levels in the blood. Except for a liver enzyme and albumin, all other molecules were found linked to the likelihood of a person becoming a centenarian. Those with increased levels of total cholesterol and iron had a greater likelihood of becoming centenarians compared to those with lower levels. However, for molecules including glucose, creatinine, uric acid, and liver enzymes, lower levels were associated with higher chances of living past 100. “We found that, on the whole, those who made it to their hundredth birthday tended to have lower levels of glucose, creatinine and uric acid from their sixties onwards,” researchers wrote in The Conversation. “Very few of the centenarians had a glucose level above 6.5 earlier in life, or a creatinine level above 125,” they said. While the differences found in the study between groups were small in some cases, researchers said the findings still suggest a “potential link” between metabolism, nutrition and longevity. However, the study falls short of recommending lifestyle factors or genes responsible for these blood molecule levels. “While chance likely plays a role for reaching age 100, the differences in biomarker values more than one decade prior death suggest that genetic and/or lifestyle factors, reflected in these biomarker levels may also play a role for exceptional longevity,” scientists wrote in the study. “However, it is reasonable to think that factors such as nutrition and alcohol intake play a role. Keeping track of your kidney and liver values, as well as glucose and uric acid as you get older, is probably not a bad idea,” they said. Read More Good financial planning could increase life expectancy, study suggests Scientists find gene that grants long life – and successfully test it on another species Scientists extend mice lives by connecting their blood to young ones

'For one, you got to make sure you get those flawless emeralds, then that piece got to go with,' said Rick Ross

Nestled within the scenic Santa Monica Mountains, a stretch of roadway known as 'The Snake' has captivated the hearts of locals and adventurers alike

Donald Trump and Ron DeSantis faced off with dueling events at Iowa’s state fair, taking their fight for

By Joey Roulette (Reuters) -Russia's space agency said on Monday that its multipurpose Nauka module attached to the International Space

London's Luton Airport has suspended all flights until Wednesday afternoon and asked passengers not to travel there after a "significant fire" caused the partial collapse...

The Parry's will visit the war-hit country to deliver further aid in their son's name.

Jake Paul's comment on girlfriend Jutta Leerdam's post left fans swooning over their relationship

Donald Trump’s $475m defamation lawsuit against CNN has been thrown out by a federal judge. The former president made the assertion that the news network’s description of his election fraud claims as the “big lie” connected him to Adolf Hitler, the leader of Nazi Germany, Reuters noted. US Judge Raag Singhal at the federal court in Fort Lauderdale, Florida, was nominated by Mr Trump in 2019. In a Friday night ruling, he said CNN’s statements were opinion and not fact, meaning that they cannot be the subject of a defamation claim. “CNN’s statements while repugnant, were not, as a matter of law, defamatory,” he wrote. A Trump spokesperson told Reuters: “We agree with the highly respected judge’s findings that CNN’s statements about President Trump are repugnant. CNN will be held responsible for their wrongful mistreatment of President Trump and his supporters.” The spokesperson didn’t indicate if Mr Trump intends to appeal the ruling. The lawsuit was filed in October of last year, citing five times that CNN published stories or broadcast comments calling Mr Trump’s claims that the 2020 election was fraudulent the “big lie” – a phrase also linked to Nazi Germany’s propaganda. The legal filing argued that it was “a deliberate effort by CNN to propagate to its audience an association between the plaintiff and one of the most repugnant figures in modern history”. The judge wrote that the use of the phrase “big lie” isn’t sufficient to establish a connection. “No reasonable viewer could (or should) plausibly make that reference,” he wrote. Since the start of his first campaign in 2015, Mr Trump has repeatedly attacked the media, with CNN being one of his main targets. In the face of indictments on both the state and federal levels, Mr Trump remains the favourite to win the 2024 Republican presidential nomination. Read More Trump indictment – live: GOP candidate booed off stage for criticising Trump as ex-president slams DeSantis ‘Poetic’: Trump takes stage in Iowa to song about going to prison GOP White House hopeful Will Hurd booed off stage for saying Trump is running to stay out of prison ‘Poetic’: Trump takes stage in Iowa to song about going to prison Ex-Missouri Gov. Jay Nixon joins push for third-party presidential bid as Democrats try to stop it Trump’s ‘Hitler’ lawsuit against CNN thrown out ahead of rally in Pennsylvania - live

By Michelle Nichols UNITED NATIONS A deal allowing the safe wartime export of grain and fertilizer from Ukrainian

Floodwaters were diverted from Beijing, but the water had to go somewhere - So Zhuozhou took the brunt.

Scot Peterson is thought to be the first US officer ever charged with failing to respond to a school shooting.