A "ring of fire" annular solar eclipse will put on a show from Oregon to Texas this Saturday -- as long as clouds don't spoil the fun.

A Florida man sentenced to death for the 1988 attack on a woman who was sexually assaulted and killed with a hammer, then set on fire in her own bed, is set for execution Thursday after dropping all his appeals and saying he was ready to die

WASHINGTON U.S. Secretary of State Antony Blinken spoke on Monday with Niger's President Mohamed Bazoum, who was ousted

While Louisiana’s gubernatorial election was decided in October, voters will cast ballot to determine a slew of runoff races including for three vacant statewide offices: attorney general, secretary of state and treasurer

Kai Cenat played the 'Would you Rather' game during a livestream interaction with fans

A missile targeted Kyiv on Saturday, ending nearly two months of relative calm in the Ukrainian capital, while frontline regions fended off waves...

A treatment for acute migraines has been approved for NHS use for the first time, with experts saying the move could be a “step-change” for thousands of people who suffer from the condition. The National Institute for Health and Care Excellence (Nice) said its final draft guidance on Rimegepant “addresses the high unmet need for treatment options for acute migraine”. Rimegepant, also known as Vydura and made by Pfizer, will be available to adults who have tried at least two triptans – medication usually given to tackle headaches or migraines – but found they did not work well enough. It can also be administered to those who are not able to take triptans or have an intolerance, or patients who have tried nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol. Helen Knight, director of medicines evaluation at Nice, said: “Migraine is a condition described in comments to Nice from carers and people with migraine as an invisible disability that affects all aspects of life including work, education, finances, mental health, social activities and family. “Today’s final draft guidance addresses the high unmet need for treatment options for acute migraine, once again demonstrating our ability to ensure clinically and cost-effective medicines are available to those who need them as quickly as possible.” Rimegepant is taken as a wafer, which dissolves under the tongue and works by stopping the release of a protein around the brain called calcitonin gene-related peptide. In July, the medicine was recommended as an option for preventing episodic migraines in adults who have at least four and fewer than 15 attacks per month if “at least” three other treatments have not worked. This is the first and only Nice-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment Helen Knight, Nice Under the latest guidance, it will also be used to relieve symptoms of a migraine, which can include pain, nausea and sensitivity to light, but also painless symptoms such as temporary visual disturbances known as “aura”, which Nice said “is not well managed with existing treatments”. The recommendation is expected to benefit about 13,000 people. Ms Knight added: “This is the first and only Nice-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment.” Migraine is an incredibly misunderstood condition that can have a significant impact on all areas of life, including ability to work, maintain relationships and mental health Robert Music, The Migraine Trust Robert Music, chief executive of The Migraine Trust, said the Nice guidance “provides people with migraine valuable options to help reduce the pain and length of a migraine attack”. “It brings new hope,” he added. “It will especially benefit those who have not found a treatment that works, those who get debilitating side effects – including medicine overuse headache – from them, and those with cardiovascular disease who cannot take existing treatments. “Migraine is an incredibly misunderstood condition that can have a significant impact on all areas of life, including ability to work, maintain relationships and mental health.” Read More NHS winter resilience fund announced by Government NHS reliance on paper notes ‘stopping trusts from realising full potential’ Recession fears as UK economy shrinks by more than expected in shock decline Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

Prominent streamers xQc and Dr DisRespect were among the first to praise Bungie's newly announced game 'Marathon'

A federal judge has declared a mistrial in the trial of a former Louisville police officer who fired stray bullets in the deadly Breonna Taylor raid

Several Virginia incumbents prevailed over challengers in a closely watching Virginia primary election

The costs related to the East Palestine derailment continue to grow to reach $966 million for Norfolk Southern, but the railroad's service is improving and its insurance companies have started to pay their share of the cost of the crash in eastern Ohio early this year

YouTubers PewDiePie and TheAnimeMan collaborated once again visiting a popular sushi restaurant in Tokyo's Tsukiji Outer Market