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Placenta abnormalities could be the reason for miscarriages, study suggests
Placenta abnormalities could be the reason for miscarriages, study suggests
A new study has found that placenta abnormalities could be the reason for miscarriages. In the United States, there are approximately 5 million pregnancies per year with 1 million ending in a miscarriage and over 20,000 ending in stillbirth, according to a paper published in the journal Reproductive Sciences. “To have a pregnancy loss is a tragedy. To be told there is no explanation adds tremendous pain for these loss families,” said senior author of the paper and research scientist at Yale School of Medicine, Dr Harvey Kliman “Our goal was to expand the current classification systems to decrease the number of cases that remained unspecified.” For the study, researchers worked to create a classification system for miscarriages based on a test that examines a sample of the body’s tissues – known as pathologic examination. The team looked at a series of 1,527 single-child pregnancies that ended in miscarriage, and the data was then sent to Yale for evaluation. After excluding cases without adequate material for examination, 1,256 placentas from 922 patients were examined. Of these, 70 per cent were miscarriages and 30 per cent were stillbirths. By adding the explicit categories of “placenta with abnormal development” (dysmorphic placentas) and “small placenta” (a placenta less than the 10th percentile for gestational age) to other incidents such as cord accident, abruption, thrombotic, and infection – researchers were able to determine the results of 91.6 per cent of the pregnancies, including 88.5 per cent of the miscarriages and 98.7 per cent of the stillbirths. The most common results for unexplained miscarriages were dysmorphic placentas (placenta with abnormal development) which was around 86.2 per cent. For stillbirths, there was 33.9 per cent due to a small placenta. “This work suggests that the over 7,000 small placentas per year associated with stillbirths could have been detected in utero — flagging those pregnancies as high risk prior to the loss,” said Dr Kliman. “Likewise, the identification of dysmorphic placentas may be one way to potentially identify genetic abnormalities in the almost 1 million miscarriages that occur in our country every year.” He said having a definite explanation “for a pregnancy loss helps the family understand that their loss was not their fault, allows them to start the healing process, and, when possible, prevent similar losses — especially stillbirths — from occurring in the future.” When asked what the most effective way might be to prevent stillbirths, Dr Kliman responded, “Measure the placenta!” Read More 'Please, keep beating little heart': Man gives raw account of wife's miscarriage and fears for new unborn child Woman who had six miscarriages celebrates pregnancy with rainbow baby photoshoot Miscarriage: The loneliest grief of all Nearly a fifth of parents fear children will ignore health issues while at university Brits feel their mental health declining due to cost of living crisis How often should you wash your pyjamas?
2023-09-19 23:50
Who was Catorreia Hutto? 5-year-old twins found dead after mother jumps off bridge in Florida
Who was Catorreia Hutto? 5-year-old twins found dead after mother jumps off bridge in Florida
Florida mother jumped to her death off a bridge, and her twins were found dead in their home in what police believes to be a case of murder-suicide
2023-10-21 16:21
Maldives president-elect says he's committed to removing the Indian military from the archipelago
Maldives president-elect says he's committed to removing the Indian military from the archipelago
The president-elect of the Maldives says he's sticking to his campaign promise to remove Indian military personnel stationed in the archipelago state, promising he will initiate the process
2023-10-03 15:24
Ludwig unveils participants' names, date and time for World's Greatest Gamer event
Ludwig unveils participants' names, date and time for World's Greatest Gamer event
Ludwig is organizing World's Greatest Gamer event where big names in the industry will take part
2023-09-02 17:47
Niger junta says France plotting to 'intervene militarily'
Niger junta says France plotting to 'intervene militarily'
Niger's new junta on Monday accused France of seeking to "intervene militarily" to reinstate deposed President Mohamed Bazoum as tension mounted with the...
2023-07-31 21:55
24-year-old driver for Tony Stewart Racing dies in interstate-highway crash
24-year-old driver for Tony Stewart Racing dies in interstate-highway crash
A 24-year-old woman who drove for Tony Stewart Racing died Friday after being ejected from the car in which she was riding on an Indiana highway.
2023-08-22 10:25
Asylum officers, Secret Service agents and troops have surged toward border with Title 42's expiration hours away
Asylum officers, Secret Service agents and troops have surged toward border with Title 42's expiration hours away
With just hours left before Title 42 expires Thursday night, the US is wrapping up a surge of asylum officers, troops and federal agents toward the southern border, anticipating the Trump-era border restriction policy's demise could spur an even heavier migrant influx than the country has already seen in recent weeks.
2023-05-11 15:26
U.S. investigates 346,000 Ford Escape SUVs over door issues
U.S. investigates 346,000 Ford Escape SUVs over door issues
U.S. auto safety investigators said Tuesday they are opening an investigation into 346,000 Ford Escape sport utility vehicles
2023-07-11 20:17
LeBron James thanks well-wishers after son Bronny's cardiac arrest
LeBron James thanks well-wishers after son Bronny's cardiac arrest
LeBron James tweeted about his son Bronny James on Thursday for the first time since the 18-year-old suffered a cardiac arrest earlier this week, thanking well-wishers for sending his family "love and prayers."
2023-07-28 01:48
'Where’s my cut?' xQc demands Kai Cenat pay him for stealing 'camping idea' worth 'at least seven-figures'
'Where’s my cut?' xQc demands Kai Cenat pay him for stealing 'camping idea' worth 'at least seven-figures'
xQc accused Kai Cenat of stealing content ideas
2023-05-29 12:25
European Stocks Rise as Anglo American Boosts Miners; ASML Drops
European Stocks Rise as Anglo American Boosts Miners; ASML Drops
European stocks gained, erasing an earlier decline, as Anglo American Plc helped lift the gauge while investors digested
2023-07-20 20:45
World leaders, activists in Paris seek financial response to climate emergency, poverty
World leaders, activists in Paris seek financial response to climate emergency, poverty
World leaders, heads of international organizations and activists are gathering in Paris for a two-day summit to seek better ways to tackle poverty and climate change issues by reshaping the global financial system
2023-06-22 12:24