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(Reuters) -At least three people were killed in Kyiv early on Saturday after Russia unleashed its latest overnight air strikes

More than 50 people have been killed – including a six-year-old boy – after a Russian missile hit a shop and cafe in northeastern Ukraine where mourners had gathered for a wake. It is one of the deadliest such attacks since Vladimir Putin launched his invasion 19 months ago. Ukrainian President Volodymyr Zelensky, who was in the southern Spanish city of Granada for a conference with European leaders at the time of the strike, described the attack as a “brutal Russian crime” and accused Moscow of "genocidal aggression". During an emotional address to the European Political Community (EPC) in Spain, he cited the devastating impact Russian strikes were having on Ukrainian children in Kharkiv Oblast, forcing them to take school lessons in makeshift classrooms underground. A short time later officials in Kyiv said a Russian Iskander missile struck the 330-person village of Hroza in the Kharkiv region, killing at least 51, including a six-year-old boy. One image of the aftermath of the strike showed a number of bodies strewn across the floor, covered in the dust kicked up by the explosion. A handful of civilians could be seen crying behind them as two ambulance workers stood nearby. The interior minister, Ihor Klymenko, said that residents of Hroza had been holding a memorial service in the cafe that was reduced to rubble by the attack. "From every family, from every household, there were people present at this commemoration. This is a terrible tragedy," Mr Klymenko told Ukrainian television. Reacting to the strike, Kira Rudik, a leading Ukrainian opposition MP, told The Independent: “You may think that we would get used to the news of our people getting killed, but everytime it is a shock.” She reiterated the calls made by Mr Zelensky throughout the summit in Spain for more air defences and weapons from Western allies, arguing that it was essential for Ukraine “particularly to protect those places so close to the front”, such as Hroza. The village sits only around 30 miles from the nearest Russian soldiers. In recent months, thousands have fled the broader Kupyansk district, in which Groza is located, as thousands of Russian troops stage an assault of their own while Kyiv continues to push ahead with its counteroffensive further south. Mr Zelensky has visited the areas around the frontlines Kharkiv in recent days, recording a message of support for the troops battling to keep Russian forces from advancing. "The terrorists deliberately carried out the attack during lunchtime, to ensure a maximum number of casualties," Ukraine's defence minister, Rustem Umerov, said. "There were no military targets there. This is a heinous crime intended to scare Ukrainians." Mr Zelensky arrived in Spain for the European Political Community (EPC) forum on Thursday morning, meeting first with the Spanish President Pedro Sanchez before holding talks with various other leaders, including UK Prime Minister Rishi Sunak, France's President Emmanuel Macron and Italian prime minister Georgia Meloni. Though multiple issues, such as energy prices, were on the agenda for the EPC forum, the issue of supporting Ukraine was the “core” topic of discussion, according to European Commission President Ursula von der Leyen. Mr Sunak reiterated Britain's long-term support for Ukraine and said that he would be encouraging European leaders to work together to supply further defensive weapons. Both Mr Zelensky and his top aide Andriy Yermak said prior to arriving in Spain that securing new air defence systems was their top priority ahead of the winter, when Russia is expected to ramp up its missile campaign on major cities across the country. Mr Zelensky told the leaders in Granada that by providing additional military equipment to Ukraine, European countries could help ensure that a "drone, tank, or any other Russian weapon will not strike anyone else in Europe". In the wake of the attack in Kharkiv, Mr Zelensky added in a social media post: "Now we are talking with European leaders, in particular, about strengthening our air defence, about strengthening our soldiers, about giving our country protection from terror". A Spanish government source later confirmed to Reuters that Mr Sanchez had heeded that call, reporting that Spain would send both an air defence and anti-drone system to Kyiv. Ahead of the summit, German media reported that German Chancellor Olaf Scholf was reluctant to donate to Ukraine long-range Taurus missiles, despite widespread pressure from his allies to do so, over fears it would escalate tensions with Russia. The chancellor is reportedly concerned that Ukraine will use the missiles, which have a range further than the British Storm Shadows, Kyiv’s longest-range weapon to date, to hit the Kerch Strait Bridge connecting Russia to the Moscow-occupied Crimean peninsula. Mr Zelensky met with Mr Scholz on Thursday, with the two leaders discussing “working on providing Ukraine with an additional ‘Patriot’ [air defence] system for the winter months”. The meeting in Granada was also a space to shore up support for Kyiv after a weekend of political turmoil in the US. A dispute among the Republican majority in the lower chamber of the US Congress has complicated spending negotiations and prompted Democrat President Joe Biden to go from confident that a deal will be made on further Ukraine aid from Washington to openly expressing concern. Mr Zelensky admitted that there was a “political storm” over Washington but said he was “confident” that it would be resolved. “They are strong people with strong institutions, and a strong democracy,” he said. “I am confident in America.” Elsewhere, at an address in the Russian resort city of Sochi, Mr Putin accused the West of losing touch with reality over the Ukraine war. In a speech that aired many of his oft-repeated grievances against Ukraine's allies over their support for Kyiv, he also held out the possibility that Russia could resume nuclear testing for the first time in over three decades and might withdraw its ratification of a landmark nuclear test ban treaty. Read More IMF chief says the global economy has show resilience in the face of COVID, war and high rates Russia has tested a nuclear-powered missile and could revoke a global atomic test ban, Putin says Live: Karine Jean-Pierre holds White House briefing as Biden vows to stand by Ukraine

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Cardio isn’t so bad if you take it in small steps. Climbing at least 50 stairs each day could significantly slash your risk of heart disease, according to a new study. The research, published in the journal Atherosclerosis, found that ascending more than five flights of stairs daily could reduce the risk of cardiovascular ailments by about 20 per cent. Cardiovascular diseases such as Atherosclerotic cardiovascular disease (ASCVD) along with coronary artery disease and strokes are the leading causes of morbidity and mortality worldwide. “Short bursts of high-intensity stair climbing are a time-efficient way to improve cardiorespiratory fitness and lipid profile, especially among those unable to achieve the current physical activity recommendations,” said co-author Dr Lu Qi, HCA Regents Chair and professor at Tulane University’s School of Public Health and Tropical Medicine in New Orleans. “These findings highlight the potential advantages of stair climbing as a primary preventive measure for ASCVD in the general population.” For the study, researchers used data from a UK Biobank of 450,000 adults and participants were analysed based on their family history of cardiovascular disease as well as their genetic risk factors and established risk factors. Participants were also asked about their lifestyle habits and their frequency of climbing stairs, with the median follow-up time being 12.5 years. The results revealed that climbing more stairs daily reduced the risk of cardiovascular disease in those who were less susceptible, with Dr Qi saying the increased risk of heart disease in more susceptible people could be “effectively offset”. “This study provides novel evidence for the protective effects of stair climbing on the risk of ASCVD, particularly for individuals with multiple ASCVD risk factors,” Dr Qi added. ‘A significant training effect’ Dr Nicolas Berger, a senior lecturer in sport and exercise at England’s Teesside University, who was not a part of the study, says walking up staircases has more benefits than walking on a flat surface because it “requires the use of more muscles as well as some balance and gross motor skills.” He says even though these may be in “short bursts”, it still “requires a lot of activity from your cardiovascular system and that is why people often find themselves out of breath whilst climbing stairs. “These short, intermittent bursts of activity have large benefits in terms of reducing the risk of cardiovascular disease. They can significantly increase your heart rate and oxygen uptake and cause positive adaptations in the body,” Dr Berger adds. Although 50 steps a day might not seem like much “it can have a significant training effect.” This type of movement activates muscles such as the glutes, quads, hamstring and calves, as well as muscles in the core, Dr Berger says. If you are not much of a runner, Dr Berger suggests taking stairs may be a useful option. “It’s an attractive alternative to just walking or running for many, due to the easy access for most people in their houses or when out. “If there are no stairs available, walking up and down steep gradients also has similar benefits and demands. Getting up off the floor or low ground has benefits in terms of strength and balance, but not so much for the cardiovascular system. “Overall, incorporating this activity into daily habits for sedentary people, people at risk or anyone trying to stay healthy is a good suggestion,” he adds. Read More How many steps a day can cut risk of early death (and it’s not 10,000) Tread carefully: Do we really need to walk 10,000 steps a day? What I gained (and lost) by walking 10,000 steps each day for 5 months Is a four-day week a good idea? | You Ask The Questions 9 science-backed ways to lose weight without going on a diet A Japanese doctor who studied longevity — and lived to 105 — said if you must retire, do it well after 65

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By Richard Cowan, Leah Douglas WASHINGTON (Reuters) -Democrats in the U.S. Congress expressed frustration with President Joe Biden's willingness to