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Placenta abnormalities could be the reason for miscarriages, study suggests
Placenta abnormalities could be the reason for miscarriages, study suggests
A new study has found that placenta abnormalities could be the reason for miscarriages. In the United States, there are approximately 5 million pregnancies per year with 1 million ending in a miscarriage and over 20,000 ending in stillbirth, according to a paper published in the journal Reproductive Sciences. “To have a pregnancy loss is a tragedy. To be told there is no explanation adds tremendous pain for these loss families,” said senior author of the paper and research scientist at Yale School of Medicine, Dr Harvey Kliman “Our goal was to expand the current classification systems to decrease the number of cases that remained unspecified.” For the study, researchers worked to create a classification system for miscarriages based on a test that examines a sample of the body’s tissues – known as pathologic examination. The team looked at a series of 1,527 single-child pregnancies that ended in miscarriage, and the data was then sent to Yale for evaluation. After excluding cases without adequate material for examination, 1,256 placentas from 922 patients were examined. Of these, 70 per cent were miscarriages and 30 per cent were stillbirths. By adding the explicit categories of “placenta with abnormal development” (dysmorphic placentas) and “small placenta” (a placenta less than the 10th percentile for gestational age) to other incidents such as cord accident, abruption, thrombotic, and infection – researchers were able to determine the results of 91.6 per cent of the pregnancies, including 88.5 per cent of the miscarriages and 98.7 per cent of the stillbirths. The most common results for unexplained miscarriages were dysmorphic placentas (placenta with abnormal development) which was around 86.2 per cent. For stillbirths, there was 33.9 per cent due to a small placenta. “This work suggests that the over 7,000 small placentas per year associated with stillbirths could have been detected in utero — flagging those pregnancies as high risk prior to the loss,” said Dr Kliman. “Likewise, the identification of dysmorphic placentas may be one way to potentially identify genetic abnormalities in the almost 1 million miscarriages that occur in our country every year.” He said having a definite explanation “for a pregnancy loss helps the family understand that their loss was not their fault, allows them to start the healing process, and, when possible, prevent similar losses — especially stillbirths — from occurring in the future.” When asked what the most effective way might be to prevent stillbirths, Dr Kliman responded, “Measure the placenta!” Read More 'Please, keep beating little heart': Man gives raw account of wife's miscarriage and fears for new unborn child Woman who had six miscarriages celebrates pregnancy with rainbow baby photoshoot Miscarriage: The loneliest grief of all Nearly a fifth of parents fear children will ignore health issues while at university Brits feel their mental health declining due to cost of living crisis How often should you wash your pyjamas?
2023-09-19 23:50
Is Travis Barker OK? Blink-182 drummer suffers severe hand injury after England concert
Is Travis Barker OK? Blink-182 drummer suffers severe hand injury after England concert
This incident adds to a series of health problems and injuries that Travis Barker has faced in recent months
2023-10-17 09:55
Hunter Biden returns to court in Delaware and is expected to plead not guilty to gun charges
Hunter Biden returns to court in Delaware and is expected to plead not guilty to gun charges
Hunter Biden is due back in a Delaware courtroom
2023-10-03 12:22
First-gen iPhone sells at auction for almost 380 times its original price
First-gen iPhone sells at auction for almost 380 times its original price
A first-generation iPhone sold at auction Sunday for $190,373, roughly 380 times its original price of $499 when it went for sale in 2007
2023-07-19 09:57
Judge rules man accused of trying to open jet's door, attacking crew, not competent for trial
Judge rules man accused of trying to open jet's door, attacking crew, not competent for trial
A federal magistrate judge has ruled that a man charged with attacking a flight attendant with a broken metal spoon and attempting to open an airliner’s emergency door on a cross-country flight in March is not currently competent to stand trial
2023-07-14 00:46
U.S. FDA panel backs Pfizer's RSV vaccine for protecting infants
U.S. FDA panel backs Pfizer's RSV vaccine for protecting infants
Advisers to the U.S. Food and Drug Administration on Thursday backed the safety and effectiveness of Pfizer Inc's
2023-05-19 05:28
New York limousine operator convicted of crash that killed 20
New York limousine operator convicted of crash that killed 20
The operator of Prestige Limousine faces 15 years in prison for failing to safety maintain the limo.
2023-05-18 10:58
Big-name Texas attorneys hired to present impeachment case against Ken Paxton
Big-name Texas attorneys hired to present impeachment case against Ken Paxton
Two prominent Texas attorneys with a long list of famous clients will present the case for impeachment against Republican Attorney General Ken Paxton
2023-06-02 06:17
Army chief nominee would boost recruiting, but Tuberville blockade leaves his confirmation uncertain
Army chief nominee would boost recruiting, but Tuberville blockade leaves his confirmation uncertain
The Army officer tapped to be the service’s next chief of staff is outlining his plan to fix what he described as the service’s top challenge — rebuilding recruiting — as it becomes clear the Army will again fall short of its enlistment goal
2023-07-13 03:17
8 Game of Thrones actors who faced personal tragedies in recent years
8 Game of Thrones actors who faced personal tragedies in recent years
A number of Game of Thrones cast members have struggled in recent years
2023-09-09 21:53
Three talking points from the Premier League weekend
Three talking points from the Premier League weekend
Manchester United's hopes of a first Premier League title for a decade have been dented just a week into the new campaign by an...
2023-08-21 08:22
Biden, US scholars accuse Trump of echoing Hitler
Biden, US scholars accuse Trump of echoing Hitler
Former US president Donald Trump faced a furious backlash Monday over Veteran's Day weekend remarks branding his political opponents "vermin," as leading scholars and President Joe Biden accused...
2023-11-14 01:50