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Centenarians tend to have lower levels of glucose, creatinine and uric acid from their sixties onwards, according to the largest study of its kind that may lead to a simple blood test to predict a person’s chance of reaching 100. The research, published on Monday in the journal GeroScience, is the biggest to date to measure and follow up the levels of different molecules in the blood of people born between 1893 and 1920. Scientists, including those from Karolinska Institutet, assessed the data on blood molecules from over 44,500 Swedes who underwent clinical testing between 1985 and 1996 and followed up till 2020. They focused specifically on people born between 1893 and 1920, who were between 64 and 99 years old when their blood samples were first tested, and followed them up as they grew closer to 100 years of age. About 1,200 individuals in the study, or about 2.7 per cent of the participants, reached 100. Researchers compared this subset’s data with those of their peers who were younger than them. The analysis found 12 blood-based molecules associated with metabolism, inflammation as well as liver and kidney function, that were also linked to ageing or mortality in previous studies. These molecules included total cholesterol and glucose as markers of metabolism, uric acid indicating inflammation levels, enzymes indicative of liver health and creatinine as a measure of kidney health. Researchers also looked at albumin and iron levels in the blood. Except for a liver enzyme and albumin, all other molecules were found linked to the likelihood of a person becoming a centenarian. Those with increased levels of total cholesterol and iron had a greater likelihood of becoming centenarians compared to those with lower levels. However, for molecules including glucose, creatinine, uric acid, and liver enzymes, lower levels were associated with higher chances of living past 100. “We found that, on the whole, those who made it to their hundredth birthday tended to have lower levels of glucose, creatinine and uric acid from their sixties onwards,” researchers wrote in The Conversation. “Very few of the centenarians had a glucose level above 6.5 earlier in life, or a creatinine level above 125,” they said. While the differences found in the study between groups were small in some cases, researchers said the findings still suggest a “potential link” between metabolism, nutrition and longevity. However, the study falls short of recommending lifestyle factors or genes responsible for these blood molecule levels. “While chance likely plays a role for reaching age 100, the differences in biomarker values more than one decade prior death suggest that genetic and/or lifestyle factors, reflected in these biomarker levels may also play a role for exceptional longevity,” scientists wrote in the study. “However, it is reasonable to think that factors such as nutrition and alcohol intake play a role. Keeping track of your kidney and liver values, as well as glucose and uric acid as you get older, is probably not a bad idea,” they said. Read More Good financial planning could increase life expectancy, study suggests Scientists find gene that grants long life – and successfully test it on another species Scientists extend mice lives by connecting their blood to young ones

Rex Heuermann’s wife has filed for divorce just six days after New York police arrested her husband over the notorious Gilgo Beach murders. Court records show that Asa Ellerup – the accused serial killer’s wife of two decades and mother of his children – filed a matrimonial complaint in Suffolk County Supreme Court on Wednesday. His family are said to have been left “shocked” and “disgusted” after the Long Island native, 59, was arrested on Thursday and charged with the murders of three women. It has now also emerged that his Manhattan-based architecture company was once hired for a project at the Trump Building in New York City. New York City Department of Buildings records obtained by real state publication The Real Deal show Mr Heuermann’s firm was hired by a third party for a $200,000 plumbing job on 40 Wall Street in 2018. “Mr Heuermann has never worked for the Trump Organization in any capacity,” a spokesperson for the Trump Organization told the outlet. “He was hired by a third-party tenant, who vacated years ago, to perform minor architectural work in their individual space.” It’s unclear whether Mr Heuermann ever visited the building. Read More Pizza crust, burner phones and his wife’s hair: How Long Island police tied Rex Heuermann to the Gilgo Beach murders Rex Heuermann’s wife ‘didn’t talk to anyone’ in Long Island community, neighbour says How the Gilgo Beach serial killer turned the Long Island shore into a graveyard Las Vegas police reviewing unsolved cold cases for links to Gilgo Beach murder suspect Rex Heuermann

(Reuters) -The U.S. Food and Drug Administration (FDA) said on Monday it had approved Sanofi and partner AstraZeneca's antibody therapy

Rayanna Brock has been arrested at least 11 times for a number of offenses ranging from shoplifting in March 2018 to terrorism-related crimes in 2020