Brazil’s players have urged their fans back in South America to stay home from work and watch them begin their Women’s World Cup campaign against Panama

The U.K. Supreme Court will start hearing arguments over whether the British government’s contentious policy to send asylum-seekers to Rwanda is lawful

The Supreme Court returns to Washington to face a new term and the fresh reality that critics increasingly view the court as a political body.

NicoleT was met with a barrage of hurtful remarks attacking her choice of swimsuit while at the beach

Scientists have grown human kidneys in pigs, for the very first time. Researchers at the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences and Wuyi University created human-pig chimeric embryos containing a combination of human and pig cells. When they transferred into 13 surrogate pig mothers, they developed kidneys that contained mostly human cells at a rate of 50 to 60 per cent, giving hope for potential transplants in the future. “Rat organs have been produced in mice, and mouse organs have been produced in rats, but previous attempts to grow human organs in pigs have not succeeded,” said the senior author Liangxue Lai. “Our approach improves the integration of human cells into recipient tissues and allows us to grow human organs in pigs.” The kidneys were not entirely human as they included vasculature and nerves made mostly from pig cells, meaning they could not be used for transplantation in their current form, but it is still a pretty impressive step. And apart from the kidneys, the embryos were dominated by pig cells, with very few human cells in the brain or central nervous system. Making brains using human and pig cells is very controversial for ethical reasons, so there are tight regulations for this kind of research. Meanwhile, pig cells tend to outcompete human cells during development, so previous experiments have created embryos that are almost entirely pig. The latest work, published in Cell Stem Cell, overcame this by genetically engineering a single-cell pig embryo so that it lacked two genes needed for kidney development. This created a gap within the embryo that could be filled by human cells. “We found that if you create a niche in the pig embryo, then the human cells naturally go into these spaces,” said Prof Zhen Dai of Guangzhou Institutes of Biomedicine and Health, another senior author. The scientists said that being able to incubate a fully human kidney inside a pig would be likely to take many years. “We would probably need to engineer the pigs in a much more complex way and that also brings some additional challenges,” said Miguel Esteban, also of the Guangzhou institute and a senior author. A central challenge would be to allow human nerves and vasculature to develop within the target organ without nerve cells developing in the central nervous system that could lead to a humanised brain. “Even theoretically it’s not clear how you’d do that,” said Ilic. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

BUCHAREST (Reuters) -Romanian President Klaus Iohannis designated Marcel Ciolacu, the leader of the ruling coalition's Social Democrat Party, as prime

Turkish President Recep Tayyip Erdogan says Russia has agreed to extend a deal that has allowed Ukraine to ship grain through the Black Sea to parts of the world struggling with hunger

Negotiators from Qatar, Egypt and the US pressed for an extension of the cease-fire agreement for Gaza that’s

A Gerber infant formula was recalled earlier this year over potential contamination of Cronobacter sakazakii, a bacteria that could cause life-threatening infections in infants

By Alexandra Ulmer Hotel entrepreneur Robert Bigelow, Republican presidential hopeful Ron DeSantis' biggest donor, is switching his support

HUZHOU, China--(BUSINESS WIRE)--Aug 20, 2023--

The Justice Department has announced a series of criminal cases tracing the illegal flow of sensitive technology, including Apple’s software code for self-driving cars and materials used for missiles, to foreign adversaries like Russia, China and Iran