California Superintendent of Public Instruction Tony Thurmond is running for governor in 2026

A lucky youngster got the birthday gift of a lifetime when she discovered a 2.95-carat golden brown diamond in Arkansas.

Canadian Prime Minister Justin Trudeau and his wife, Sophie Gregoire Trudeau, say they are separating after 18 years of marriage

US-born basketball player Kyle Anderson will play for China at next month's FIBA World Cup after obtaining Chinese nationality, Anderson and the Chinese Basketball Association (CBA) announced Monday.

A treatment for acute migraines has been approved for NHS use for the first time, with experts saying the move could be a “step-change” for thousands of people who suffer from the condition. The National Institute for Health and Care Excellence (Nice) said its final draft guidance on Rimegepant “addresses the high unmet need for treatment options for acute migraine”. Rimegepant, also known as Vydura and made by Pfizer, will be available to adults who have tried at least two triptans – medication usually given to tackle headaches or migraines – but found they did not work well enough. It can also be administered to those who are not able to take triptans or have an intolerance, or patients who have tried nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol. Helen Knight, director of medicines evaluation at Nice, said: “Migraine is a condition described in comments to Nice from carers and people with migraine as an invisible disability that affects all aspects of life including work, education, finances, mental health, social activities and family. “Today’s final draft guidance addresses the high unmet need for treatment options for acute migraine, once again demonstrating our ability to ensure clinically and cost-effective medicines are available to those who need them as quickly as possible.” Rimegepant is taken as a wafer, which dissolves under the tongue and works by stopping the release of a protein around the brain called calcitonin gene-related peptide. In July, the medicine was recommended as an option for preventing episodic migraines in adults who have at least four and fewer than 15 attacks per month if “at least” three other treatments have not worked. This is the first and only Nice-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment Helen Knight, Nice Under the latest guidance, it will also be used to relieve symptoms of a migraine, which can include pain, nausea and sensitivity to light, but also painless symptoms such as temporary visual disturbances known as “aura”, which Nice said “is not well managed with existing treatments”. The recommendation is expected to benefit about 13,000 people. Ms Knight added: “This is the first and only Nice-recommended medicine that can help alleviate the misery of acute migraines, and may be considered a step-change in treatment.” Migraine is an incredibly misunderstood condition that can have a significant impact on all areas of life, including ability to work, maintain relationships and mental health Robert Music, The Migraine Trust Robert Music, chief executive of The Migraine Trust, said the Nice guidance “provides people with migraine valuable options to help reduce the pain and length of a migraine attack”. “It brings new hope,” he added. “It will especially benefit those who have not found a treatment that works, those who get debilitating side effects – including medicine overuse headache – from them, and those with cardiovascular disease who cannot take existing treatments. “Migraine is an incredibly misunderstood condition that can have a significant impact on all areas of life, including ability to work, maintain relationships and mental health.” Read More NHS winter resilience fund announced by Government NHS reliance on paper notes ‘stopping trusts from realising full potential’ Recession fears as UK economy shrinks by more than expected in shock decline Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

The Bank of England has warned firms offloading pensions in a multibillion-pound market that they need to improve

Sharon Robinson, 40, allegedly told one Colorado venue it would get “shot up like Club Q”.

Zimbabwean President Emmerson Mnangagwa says last month's elections are a sign of the country’s “mature democracy.”

Nick Cannon has revealed the appreciation he has for ex-wife Mariah Carey during a difficult time. In a recent interview on the Diary Of A CEO podcast, the father of 12 wasn’t afraid to confess that he wouldn’t have survived his 2012 lupus diagnosis if it wasn’t for the “Without You” singer by his side. “She was my rock,” he admitted. “She went hard. To be honest, I probably wouldn’t be alive if it wasn’t for how hard she went with the doctors, with me, my stubbornness.” The Grammy winner, 54 and the former America’s Got Talent host, 42, saw sparks flying almost immediately when Carey cast Cannon as her love interest in the 2008 “Bye Bye” music video. It only took six weeks from the time they got engaged for Carey and Cannon to tie the knot. In 2011, they welcomed fraternal twins Moroccan and Monroe. Unfortunately, Cannon was diagnosed with lupus one year later - an inflammatory disease which occurs when the immune system attacks its own tissues. The Masked Singer host described Carey as “the perfect helpmate, the perfect matriarch, the perfect mom, the perfect wife” during this time. “It probably took a toll on us just because of the person I was in my head and the struggles that I was dealing with,” he continued. “But it definitely brought us closer together.” When podcast host Steven Bartlett asked whether Cannon believed Carey “saved his life”, he simply responded: “I absolutely do.” “But that’s what you do when you find a helpmate. When you find someone that you’re in matrimony with, you go hard for [them],” Cannon pointed out. “I feel like I went hard for her and we’ll still go hard - I lay down my life for her today. That’s what you do, it’s just family.” Cannon went on to explain how his experience with the disease put many things into perspective for him. However, it wasn’t easy for him to see things clearly while he was struggling. In fact, he told Bartlett that he was also dealing with mental health issues at the time, such as questioning his purpose and effect on the world. “Staring up from the hospital bed, staring at the ceiling all alone when everybody else is kicked out, and you gotta be face to face with your higher power, asking all those tough questions. Am I done?” he explained. “A lot of people don’t do that because we get caught up in the constant race of just living day to day, but it slowed down for me on many occasions.” While it may have been difficult for him to comprehend at the time, Cannon said he now lives his days with direction and without fear. “I’m probably reminded of my physical mortality all the time,” he noted. “And when you’re not afraid of dying, you focus on living, you know?” This isn’t the first time the TV personality has praised the “All I Want for Christmas Is You” singer. In 2022, Cannon opened up to Entertainment Tonight about the gratitude he has for his time spent with Carey. “I was talking about the fantasy of it all. I was like: ‘Yo, if I could have that same vibe of where I was at that state in my life and that age, of course I would do that all over again,’” he said. “But I’m not.” In addition to his two children with Carey, Cannon has welcomed Rise, Powerful, and Golden, with Brittany Bell; Zion, Zillion, and Beautiful with Abby De La Rosa; Halo with Alyssa Scott; Legendary with Bre Tiesi; and Onyx with LaNisha Cole. Cannon and Scott lost their baby boy, Zen, to cancer in 2021 when he was only five months old. Read More Nick Cannon’s brother says he can’t remember the 12 names of his nieces and nephews Nick Cannon shares Mariah Carey’s ‘high frequency’ reaction to actor having 12 children Mariah Carey: 'Music was my escape' The best napping method to help with pulling an all-nighter Toys children play with can have an effect on their success in adulthood Summer of female sporting events inspires millions of women to get back into the game

Best Buy Co. posted stronger-than-expected profits, but reported a deeper-than-expected drop in revenue for the fiscal third quarter as shoppers continue to pull back on buying gadgets in an uncertain economy

VISTA, Calif.--(BUSINESS WIRE)--May 11, 2023--

A veteran homicide detective wept in court as he testified about the 2018 massacre at a Parkland, Florida, high school