Ovidio Guzman Lopez will be prosecuted for allegedly smuggling huge quantities of methamphetamine and fentanyl across the border into the US

Joe Rogan's guest Oliver Anthony spoke about how porn addiction is a 'destructive rabbit hole' that ends up 'ruining marriages' and harming people

Alexa Nikolas has claimed that Jonah Hill 'slammed me onto the door and shoved his tongue down my throat' during a party when she was just 16

Emmie Sperandeo seems to have gone offline for good after a very bad accident

The 2024 GOP presidential debate stage is shrinking after the Republican National Committee announced late Monday that seven candidates are set to participate in the second debate -- down one from their first clash.

The rally sweeping across global bond markets received a boost on Wednesday amid mounting signs price pressures are

Google says it has made a significant step in identifying disease-causing genes, which could help spot rare genetic disorders. A new model named AlphaMissense is able to confidently classify 89 per cent of all possible “missense” variants in genes, identifying whether they are likely to cause diseases or benign. That compares with just 0.1 per cent of all missense variants that have been confidently classified by human experts. Missense variants happen when a single letter is substituted in the DNA, which in turn leads to proteins with a different amino acid. That small change can have significant effects – Google likened it to the way that changing a letter in one word can change the meaning of the whole sentence. Most of those variants are benign: the average person has more than 9,000 of them. But some of them can be disastrous, leading to rare genetic diseases. The new AlphaMissense looked at existing information about missense variants, and how commonly they are seen in humans and closely-related primates. It looked for those that were rarely seen, classifying them as pathogenic, and from that was able to use that information to analyse other protein sequences – giving not just a verdict on whether they were likely to cause problems, but also how confident it was. Experiments, conducted by humans, which look to find those mutations are expensive and slow: they require people to examine each unique protein and designed separately. Google says that the new system means that researchers can “preview” those results for thousands of proteins at a time, helping them decide where to focus. The company has used its systems to release a vast catalogue of “missense” mutations, so that researchers can learn about what effect they have. In some cases, those variations can lead to conditions such as cystic fibrosis, sickle-cell anaemia, or cancer, and understanding them could be key to researchers studying ways to treat or prevent those diseases. It is just the latest health breakthrough from Google’s Deepmind division, which is looking to use artificial intelligence to both identify and treat a variety of conditions. The new system was built on AlphaFold, the breakthrough model that helped unfold proteins, the building blocks of life. The research is described in a new paper, ‘Accurate proteome-wide missense variant effect prediction with AlphaMissense’, published in the journal Science. The catalogue is being made “freely available to the research community”, Google said, and the company will release the code behind the AI system. Read More BBC removes some Russell Brand content as monetisation suspended on YouTube Google Bard can now link to Gmail and other apps to help with responses Long-form video content is here to stay, says YouTube UK boss

Forty-five bags containing human remains with characteristics matching seven missing call center staff has been discovered in a ravine in a suburb of Guadalajara, according to the state prosecutor's office in Jalisco.

Actor Patrick Dempsey was recently crowned the 'Sexiest Man Alive' for 2023

During an Instagram Live session, the rapper expressed her enthusiasm about releasing music independently

Japan’s biggest life insurers have ramped up their use of longer-dated currency hedges to a record to escape

LeBron James says his family is “safe and healthy” three days after his oldest son, Bronny, went into cardiac arrest