'GMA' host Ginger Zee shared that she took the 'no new clothes' challenge seriously and didn't buy new clothes since June 2022

Prominent North Carolina civil rights leader Bishop William J. Barber II delivered his final sermon as the pastor of Greenleaf Christian Church as he retired after 30 years.

A man stabbed a pit bull to death in New York City’s Central Park after a verbal dispute with the dog’s owner

Three men face federal charges for allegedly vandalizing homes associated with two New Hampshire journalists, authorities said, in suspected acts of retaliation for a published article.

Google says it has made a significant step in identifying disease-causing genes, which could help spot rare genetic disorders. A new model named AlphaMissense is able to confidently classify 89 per cent of all possible “missense” variants in genes, identifying whether they are likely to cause diseases or benign. That compares with just 0.1 per cent of all missense variants that have been confidently classified by human experts. Missense variants happen when a single letter is substituted in the DNA, which in turn leads to proteins with a different amino acid. That small change can have significant effects – Google likened it to the way that changing a letter in one word can change the meaning of the whole sentence. Most of those variants are benign: the average person has more than 9,000 of them. But some of them can be disastrous, leading to rare genetic diseases. The new AlphaMissense looked at existing information about missense variants, and how commonly they are seen in humans and closely-related primates. It looked for those that were rarely seen, classifying them as pathogenic, and from that was able to use that information to analyse other protein sequences – giving not just a verdict on whether they were likely to cause problems, but also how confident it was. Experiments, conducted by humans, which look to find those mutations are expensive and slow: they require people to examine each unique protein and designed separately. Google says that the new system means that researchers can “preview” those results for thousands of proteins at a time, helping them decide where to focus. The company has used its systems to release a vast catalogue of “missense” mutations, so that researchers can learn about what effect they have. In some cases, those variations can lead to conditions such as cystic fibrosis, sickle-cell anaemia, or cancer, and understanding them could be key to researchers studying ways to treat or prevent those diseases. It is just the latest health breakthrough from Google’s Deepmind division, which is looking to use artificial intelligence to both identify and treat a variety of conditions. The new system was built on AlphaFold, the breakthrough model that helped unfold proteins, the building blocks of life. The research is described in a new paper, ‘Accurate proteome-wide missense variant effect prediction with AlphaMissense’, published in the journal Science. The catalogue is being made “freely available to the research community”, Google said, and the company will release the code behind the AI system. Read More BBC removes some Russell Brand content as monetisation suspended on YouTube Google Bard can now link to Gmail and other apps to help with responses Long-form video content is here to stay, says YouTube UK boss

Kendall Jenner says it's 'weird' to fall under the umbrella of the Kardashian sisters as she's so much like her dad Caitlyn Jenner

MOSCOW A vast Soviet-era dam in the Russian controlled part of southern Ukraine was blown on Tuesday, unleashing

Jacksonville's sheriff says a white gunman who killed three people at a Dollar General store Saturday was racially motivated and hated Black people

The website of the port of Rotterdam was targeted in a cyberattack blamed on Russia-aligned hackers last week.

Cuba is reaffirming its alliance with Russia through a series of agreements considered key for the island nation, including on oil and fuel supply, the sale of wheat and the resumption of flights between both countries

Paige Spiranac made a playful claim regarding her role in the American Ryder Cup struggles on European turf

Australia’s online safety watchdog has issued a legal notice to Twitter demanding an explanation of what the social media giant is doing to tackle a surge in online hate since Tesla CEO Elon Musk bought the platform